Codeine: In people getting MAO inhibitors, an First smaller check dose is recommended to allow observation of any abnormal narcotic consequences or MAOI conversation.
This merchandise may incorporate inactive substances, which can trigger allergic reactions or other troubles. Discuss with your pharmacist for more aspects.
If an individual has overdosed and it has significant indicators for instance passing out or issues respiratory, get in touch with 911. Otherwise, simply call a poison Regulate Middle immediately.
Resuscitation may very well be demanded (see OVERDOSAGE). Confined knowledge counsel that use of promethazine hydrochloride all through labor and shipping does not have an considerable impact on the duration of labor or supply and does not raise the risk of need for intervention within the new child.
As a consequence of inconsistencies concerning the drug labels on DailyMed along with the capsule images supplied by RxImage, we not Show the RxImage pill photos related to drug labels.
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In case you are prescribed this medication on a daily routine and miss a dose, just take it the moment you try to remember. Whether it is close to the time of the subsequent dose, skip the missed dose. Acquire your future dose with the frequent time. Will not double the dose to capture up.
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These little ones may be specially Promethazine codeine syrup delicate to the respiratory depressant consequences of codeine which has been speedily metabolized to morphine. Codeine is contraindicated for article-operative suffering management in these clients (see WARNINGS – Dying Connected with Ultra-Swift Metabolism of Codeine to Morphine and CONTRAINDICATIONS). Excessively huge dosages of antihistamines, like promethazine hydrochloride, in pediatric people may perhaps bring about unexpected Dying (see OVERDOSAGE). Hallucinations and convulsions have happened with therapeutic doses and overdoses of promethazine hydrochloride in pediatric clients. In pediatric individuals who are acutely unwell associated with dehydration, You can find an increased susceptibility to dystonias with the use of promethazine HCl.
Promethazine is properly absorbed from your gastrointestinal tract. Clinical results are evident inside of twenty minutes immediately after oral administration and generally very last 4 to six several hours, Despite the fact that They could persist so long as 12 hours. Promethazine is metabolized with the liver to many different compounds; the sulfoxides of promethazine and N-demethylpromethazine are definitely the predominant metabolites showing within the urine.
The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric people a lot less than 6 a long time of age, because the combination may lead to fatal respiratory melancholy During this age population.
Most MAO inhibitors also needs to not be taken for 2 weeks just before treatment method with this medication. Check with your physician when to start or prevent using this medication.
Carefully evaluate the dose employing a Unique measuring machine/spoon. Tend not to make use of a house spoon since you may well not get the proper dose.
This is simply not a whole listing of achievable side effects. If you recognize other Unwanted side effects not shown earlier mentioned, Make contact with your physician or pharmacist.